One of the most commonly used drugs is 18 F-FDG (Fluorodeoxyglucose), which has a relatively short half life of about 110 minutes.
Other medicines used in this facility:
- 68Ga-DOTA-peptides (TOC, TATE, and NOC):
The above-mentioned drugs are a group of PET materials specifically attached to Somatostatin (SST) receptors that are highly expressed in neuroendocrine tumors (NET). PET/CT scans are much more effective than CT for demonstrating neuroendocrine tumors in patients.
Clinical studies have also demonstrated the superiority of this type of PET in comperisem to the pentetreotide-SPECT scan to examine neuroendocrine tumors (NET) metastases and to find primary tumors.
68Ga-DOTA-TATE can also find the location of neural bladder tumors, such as paraganglioma, with more efficiency than MIBG.
The prostatic specific membrane antigen (PSMA) is a specific glycoprotein that is highly expressed on the surface of the prostatic cells. In recent years, 68Ga has been used to label this antigen for diagnosis and 177Lu for treatment. At the level of PSA > 2.2, the detection rate of the prostate masses by this scan is approximately 100%.
- 18F-FDG PET/CT Indications